… a dozen groups of Native Americans. Charleston was founded in … During the 1600s, some Native American tribes aided the European … European settlers caused the Native Americans of the Lowcountry to … area and beyond. The Native Americans of the Lowcountry are …… a dozen groups of Native Americans. Charleston was founded in … During the 1600s, some Native American tribes aided the European … European settlers caused the Native Americans of the Lowcountry to … area and beyond. The Native Americans of the Lowcountry are …