… the U.S., American Indian and Alaska Native (AI/AN … more dramatic among Native American and Hispanic… deaths of despair” affect Native Americans differently than white communities … economic conditions for Native Americans has gone largely unexamined …… the U.S., American Indian and Alaska Native (AI/AN … more dramatic among Native American and Hispanic… deaths of despair” affect Native Americans differently than white communities … economic conditions for Native Americans has gone largely unexamined …